Serotonin and Norepinephrine Reuptake Inhibitors are used to treat depression.
Serotonin norepinephrine reuptake inhibitors (SNRIs) inhibit the reuptake of serotonin and norepinephrine at the level of the synapse. This class of antidepressant drugs are used to treat depression, anxiety, obsessive-compulsive disorder (OCD), neuropathic pain, and other conditions.
SNRIs increase the levels of the mood related neurotransmitters serotonin and norepinephrine. In contrast, the more widely used SSRI antidepressants only increase serotonin levels.
| Medication Name |
Generic Available |
Discount Programs |
| Duloxetine (Cymbalta) |
No |
Patent expires in 2013 |
Venlafaxine (Effexor,
Effexor XR) |
Yes |
|
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Nonbenzodiazepine Hypnotics are used to treat insomnia.
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SSRIs (Selecive Serotonin Reuptake Inhibitors) are selective serotonin reuptake inhibitors used to treat depression, anxiety , and other disorders.
SSRIs increase serotonin levels by inhibiting the reuptake of serotonin into the presynaptic cell. This increases the serotonin available to bind to the postsynaptic serotonin receptor.
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Dopamine reuptake inhibitors are used to treat depression and for smoking cessation. Bupropion is the only member of this class marketed in the USA.
Bupropion is an atypical antidepressant that inhibits the reuptake of norepinephrine and dopamine. Bupropion is also a nicotinic antagonist.
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