Calcium Channel Blockers are used to treat hypertension and heart rhythm disturbances.
Calcium channel blockers inhibit the voltage-gated calcium channels (VGCCs) of cardiac and vascular smooth muscle. This reduces cardiac contractility and vascular smooth muscle tone. These two actions result in a decreased blood pressure.
*Also contains Trandolapril
**Also contains Benazepril
***Also includes Atorvastatin
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ACE-Is (Angiotensin Converting Enzyme Inhibitors) are used to treat hypertension and congestive heart failure. ACE-Is have been shown to reduce the risk of death in patients with CHF.
*Also contains hydrochlorothiazide
** Also contains verapamil
*** Also contains felodipine
**** Also contains amlodipine
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Angiotensin II receptor blockers (ARBs) inhibit the renin-angiotensin-aldosterone system at the level of the Angiotensin II AT1-receptor. ARBs are used to treat high blood pressure, diabetic nephropathy, and congestive heart failure.
No generic ARBs are approved at this time.
In 2010, the patents for Eprosartan, Irbesartan, and Losartan will expire.
*Also contains hydrochlorothiazide
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