Archive

Posts Tagged ‘Antidepressant’

Serotonin and Norepinephrine Reuptake Inhibitors

May 22nd, 2009

Serotonin and Norepinephrine Reuptake Inhibitors are used to treat depression.

Serotonin norepinephrine reuptake inhibitors (SNRIs) inhibit the reuptake of serotonin and norepinephrine at the level of the synapse.  This class of antidepressant drugs are used to treat depression, anxiety, obsessive-compulsive disorder (OCD), neuropathic pain, and other conditions.

SNRIs increase the levels of the mood related neurotransmitters serotonin and norepinephrine.  In contrast, the more widely used SSRI antidepressants only increase serotonin levels.

Medication Name Generic Available Discount Programs
Duloxetine (Cymbalta) No Patent expires in 2013
Venlafaxine (Effexor,
Effexor XR)
Yes


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Dopamine-Reuptake Inhibitors

May 21st, 2009

Dopamine reuptake inhibitors are used to treat depression and for smoking cessation.  Bupropion is the only member of this class marketed in the USA.

Bupropion is an atypical antidepressant that inhibits the reuptake of norepinephrine and dopamine.  Bupropion is also a nicotinic antagonist.

Medication Name Generic Available Discount Programs
Bupropion (Wellbutrin, Zyban) No Patent expires in 2013


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