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Antihistamines

May 21st, 2009

Antihistamines are used to treat allergy symptoms.

Antihistamines (histamine antagonist) block the action of histamine at the H1 and H2 histamine receptors.  Antihistamines that primarily block the H1 receptor are used to treat allergies.

Allergens interact with immune cells to cause the release of histamine, which binds to the H1 receptor on other cells to produce the symptoms of an allergic reaction.

Inhibition of histamine binding to target cells reduces allergic symptoms.

Medication Name Generic Available Discount Programs
Cetirizine (Zyrtec, Zyrtec-D*) Yes OTC
Desloratadine (Clarinex, Clarinex-D*) No Patent expires in 2014
Fexofenadine (Allegra, Allegra-D*) No Patent expires in 2012
Levocetirizine (Xyzal) No Patent expires in 2012
Loratadine (Claritin, Claritin-D*) Yes OTC | Walmart | Target | Kroger

*Also contains Pseudoephedrine

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