Leukotriene Receptor Antagonists
May 10th, 2009
Leukotriene Receptor Antagonists are used to treat asthma and allergies.
No generic Leukotriene Receptor Antagonists are available.
The patent for Zafirlukast (Accolate) expires in 2011, and the patent for Montelukast (Singulair) expires in 2012.
Leukotriene antagonists block the inflammatory cascade by inhibiting the action of cysteinyl leukotrienes at CysLT1 receptors in bronchial smooth muscle and other tissues.
The action of leukotriene antagonists have been shown to improve asthma and seasonal allergy symptoms, reduce asthma exacerbations, and limit markers of inflammation such as eosinophil counts in the peripheral blood and bronchoalveolar lavage fluid.
| Medication Name | Generic Available | Discount Programs |
| Montelukast (Singulair) | No | The Singular patent expires in 2012 |
| Zafirlukast (Accolate) | No | The Accolate patent expires in 2011 |
