Archive

Archive for May, 2009

Long Acting Beta-2 Agonists

May 22nd, 2009

Long Acting Beta-2 Agonists are bronchodilators used to treat asthma and COPD.

Medication Name Generic Available Discount Programs
Arformoterol (Brovana) No The Bronava patent expires in 2012
Formoterol (Foradil,
Perforomist, Symbicort*)
No The Foradil patent expires in 2017
Salmeterol (Advair**,
Serevent)
Yes

*Also contains Budesonide
**Also contains Fluticasone

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Thyroid Hormone Replacements

May 22nd, 2009

Thyroid Hormone Replacements are used to treat hypothyroidisim.

Thyroid hormone increases the basal metabolic rate, protein synthesis, and sensitivity to catecholamines.  Thyroid hormone is released primarily at T4 from the thyroid and converted in circulation to the more active T3.  Levothyroixine is synthetic T4, and Liothyronine is synthetic T3.

Medication Name Generic Available Discount Programs
Levothyroxine
(Levothroid, Levoxyl,
Synthroid, Unithroid)
Yes Walmart | Target | Kroger | KMart
Liothyronine (Cytomel,
Triostat)
Yes

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Serotonin and Norepinephrine Reuptake Inhibitors

May 22nd, 2009

Serotonin and Norepinephrine Reuptake Inhibitors are used to treat depression.

Serotonin norepinephrine reuptake inhibitors (SNRIs) inhibit the reuptake of serotonin and norepinephrine at the level of the synapse.  This class of antidepressant drugs are used to treat depression, anxiety, obsessive-compulsive disorder (OCD), neuropathic pain, and other conditions.

SNRIs increase the levels of the mood related neurotransmitters serotonin and norepinephrine.  In contrast, the more widely used SSRI antidepressants only increase serotonin levels.

Medication Name Generic Available Discount Programs
Duloxetine (Cymbalta) No Patent expires in 2013
Venlafaxine (Effexor,
Effexor XR)
Yes


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Bisphosphonates

May 22nd, 2009

Bisphosphonates are used to treat and prevent osteoporosis.

Bisphosphonates inhibit the breakdown of bone by osteoclasts by encouraging osteoclast apoptosis.  The inhibition of osteoclasts shifts the balance of bone creation and breakdown to promote formation of new bone.

Medication Name Generic Available Discount Programs
Alendronate (Fosamax) Yes Walmart | Giant Eagle | Kroger | Giant Foods
Ibandronate (Boniva) No The Boniva patent expires in 2012
Risedronate (Actonel) No The Actonel patent expires in 2012

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Calcium Channel Blockers

May 22nd, 2009

Calcium Channel Blockers are used to treat hypertension and heart rhythm disturbances.

Calcium channel blockers inhibit the voltage-gated calcium channels (VGCCs) of cardiac and vascular smooth muscle.  This reduces cardiac contractility and vascular smooth muscle tone.  These two actions result in a decreased blood pressure.

Medication Name Generic Available Discount Programs
Amlodipine  (Norvasc,
Lotrel**, Caduet**)
Yes
Diltiazem (Cardizem,
Tiazac)
Yes Walmart | Target | Kroger | KMart
Isradipine (Dynacirc) Yes
Nicardipine (Cardene) Yes KMart
Nifedipine (Adalat) Yes
Nisoldipine (Sular) Yes
Verapamil (Isoptin,
Tarka*, Covera-HS,
Verelan PM)
Yes Walmart | Target | Kroger | KMart

*Also contains Trandolapril
**Also contains Benazepril
***Also includes Atorvastatin

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